Detalhe da pesquisa
1.
Uridine-derived ribose fuels glucose-restricted pancreatic cancer.
Nature
; 618(7963): 151-158, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37198494
2.
Iron regulates the quiescence of naive CD4 T cells by controlling mitochondria and cellular metabolism.
Proc Natl Acad Sci U S A
; 121(17): e2318420121, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38621136
3.
Cancer SLC43A2 alters T cell methionine metabolism and histone methylation.
Nature
; 585(7824): 277-282, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32879489
4.
Deep annotation of untargeted LC-MS metabolomics data with Binner.
Bioinformatics
; 36(6): 1801-1806, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31642507
5.
A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics.
Metabolomics
; 15(7): 103, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31289941
6.
Glutaminase deficiency in rod photoreceptors disrupts nonessential amino acid levels to activate the integrated stress response and induce rapid degeneration.
bioRxiv
; 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38586045
7.
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression.
Cancer Res Commun
; 4(5): 1174-1188, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38626341
8.
Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma.
Cancer Metab
; 12(1): 11, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38594734
9.
A metabolic atlas of mouse aging.
bioRxiv
; 2024 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38746230
10.
Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice.
J Clin Invest
; 134(3)2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38085578
11.
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression.
bioRxiv
; 2023 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37503050
12.
Adaptive rewiring of purine metabolism promotes treatment resistance in H3K27M-mutant diffuse midline glioma.
Res Sq
; 2023 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37790517
13.
Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer.
Cell Metab
; 35(1): 134-149.e6, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36528023
14.
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
Nat Cancer
; 4(5): 648-664, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37169842
15.
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Cancer Discov
; 13(11): 2370-2393, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37584601
16.
Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway.
Elife
; 112022 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35156921
17.
OXPHOS promotes apoptotic resistance and cellular persistence in TH17 cells in the periphery and tumor microenvironment.
Sci Immunol
; 7(77): eabm8182, 2022 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36399539
18.
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
Elife
; 112022 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35815941
19.
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells.
Nat Cancer
; 3(11): 1386-1403, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36411320
20.
HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
J Clin Invest
; 131(12)2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33914705